Among patients coinfected with HIV and hepatitis C, cannabis use reduced the risk for insulin resistance, according to researchers from INSERM in France.
“This is the first longitudinal study documenting the relationship between the reduced risk of insulin resistance and cannabis use in a population particularly concerned by insulin resistance risk,” the researchers wrote in Clinical Infectious Diseases. “The results found were robust as they were confirmed in three sensitivity analyses, one of [these] also including patients with diabetes.”
M. Patrizia Carrieri, PhD, and colleagues evaluated data from the ANRS HEPAVIH CO-13 cohort, which included patients in France coinfected with HIV and HCV. The data included patient information obtained from self-administered questionnaires, such as HIV and HCV testing, HIV-related symptoms, coffee consumption and drug and alcohol use in the previous month. The questionnaires were completed every 12 months for 60 months.
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Showing posts with label insulin resistance. Show all posts
Showing posts with label insulin resistance. Show all posts
Tuesday, March 24, 2015
Friday, February 13, 2015
Depression not linked to insulin resistance in patients with diabetes, HCV
Depression was not associated with peripheral insulin resistance among a cohort of patients with diabetes and hepatitis C virus infection, according to a study data published in the Journal of Viral Hepatitis.
Researchers enrolled 74 patients with diabetes (non-type 2) and HCV (mean age, 48 years) in the cross-sectional study and evaluated data after extensive comprehensive, clinical, histologic and metabolic testing to determine whether insulin resistance was associated with depression. Insulin was appraised through an insulin resistance test that measured steady-state plasma glucose and logistic regression analyses was used to evaluate predictors associated with depression, according to the research.
“Depression was not associated with [insulin resistance] in our HCV-infected cohort,” the researchers concluded. “With the introduction of highly effective direct-acting anti-HCV treatments, the burden of HCV is anticipated to decrease significantly. However, considering the multifactorial nature of depression, interventions directed at other modifiable risk factors in at-risk individuals in this population are warranted.”
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Researchers enrolled 74 patients with diabetes (non-type 2) and HCV (mean age, 48 years) in the cross-sectional study and evaluated data after extensive comprehensive, clinical, histologic and metabolic testing to determine whether insulin resistance was associated with depression. Insulin was appraised through an insulin resistance test that measured steady-state plasma glucose and logistic regression analyses was used to evaluate predictors associated with depression, according to the research.
“Depression was not associated with [insulin resistance] in our HCV-infected cohort,” the researchers concluded. “With the introduction of highly effective direct-acting anti-HCV treatments, the burden of HCV is anticipated to decrease significantly. However, considering the multifactorial nature of depression, interventions directed at other modifiable risk factors in at-risk individuals in this population are warranted.”
Read more...
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